Clinical Aspects of Interferons

I Clinical Uses in Infectious and Immune Diseases. - 1. Intranasal Interferons for Control of Respiratory Viral Infections. - 2. Interferon Therapy of Herpes Simplex Dermal Infections and Papillomavirus Condylomata. - 3. Interferon Therapy in Acute Viral Illnesses. - 4. Kaposi's Sarcoma and AIDS: The Role of Interferons in Treatment. - 5. Use of Interferon in the Treatment of Subacute Sclerosing Panencephalities. - 6. Multiple Sclerosis: Clincial Trials with Interferons. - 7. The Promise of Interferon Therapy for Parasitic Diseases. - II Clinical Uses in Cancer. - 8. Interferon Treatment of Non-Hodgkin's Lymphoma and Myeloma: A Model for Biotherapy. - 9. The Role of Interferon Alpha in the Treatment of Hairy Cell Leukemia (HCL). - 10. Clinical Studies of Alpha and Gamma Interferons in Chronic Myelogenous Leukemia. - 11. Interferon Therapy of Chronic Lymphocytic Leukemia and Viral Infections in Leukemia Patients. - 12. Interferons in the Treatment of Metastatic Renal Cell Carcinoma. - 13. Interferons in Breast Cancer. - 14. Osteosarcoma Management and Interferon. - 15. Clinical Use of Interferons in the Treatment of Malignant Brain Tumors. - 16. Interferon Treatment of Neuro-Endocrine Tumors of Pancreas and Gut. - 17. The Role of Beta Interferon in the Treatment of Cervical Dysplasia. - 18. Interferons in Combination with Cytotoxic Modalities for Cancer Treatment. - III Biological Properties and Experimental Systems. - 19. Toxic Effects. - 20. Pharmacokinetics of Interferons and Practical Implications. - 21. Monitoring of Interferon Therapy by Assay of Interferon-Induced (2 ??5?) Oligo A Synthetase in Human Peripheral White Blood Cells. - 22. Interferon Studies in Non-Human Primates. - 23. Animal Model Systems to Evaluate the Antitumor Activity of Interferons. - 24. Effects ofPolynucleotides on Monkeys and Man. - 25. Delivery of Interferons to Target Cells by Monoclonal Antibodies: Potential for the Specific Targeting of Other Lymphokines. - 26. Immunomodulatory Actions of Interferons. - 27. Synergistic Actions of Interferons and Tumor Necrosis Factor. Language: English