When Rats Lice and History appeared in 1935 Hans Zinsser was a highly regarded Harvard biologist who had never written about historical events. Although he had published under a pseudonym virtually all of his previous writings had dealt with infections and immunity and had appeared either in medical and scientific journals or in book format. Today he is best remembered as the author of Rats Lice and History which gone through multiple editions and remains a masterpiece of science writing for a general readership. To Zinsser scientific research was high adventure and the investigation of infectious disease a field of battle. Yet at the same time he maintained a love of literature and philosophy. His goal in Rats Lice and History was to bring science philosophy and literature together to establish the importance of disease and especially epidemic infectious disease as a major force in human affairs. Zinsser cast his work as the biography of a disease. In his view infectious disease simply represented an attempt of a living organism to survive. From a human perspective an invading pathogen was abnormal; from the perspective of the pathogen it was perfectly normal. This book is devoted to a discussion of the biology of typhus and history of typhus fever in human affairs. Zinsser begins by pointing out that the louse was the constant companion of human beings. Under certain conditionsâto wash or to change clothingâlice proliferated. The typhus pathogen was transmitted by rat fleas to human beings who then transmitted it to other humans and in some strains from human to human. Rats Lice and History is a tour de force. It combines Zinsser's expertise in biology with his broad knowledge of the humanities . Language: English